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Significant weight gain has been reported with the use of INVEGA SUSTENNA®.
Clinical monitoring of weight gain is recommended.1
*Initial deltoid injection of 234 followed by 39 mg, 156 mg, or 234 mg every 4 weeks by deltoid or gluteal injection.
Other dose groups (39 mg, 78 mg, and 156 mg) are from studies involving only gluteal injection.1
Results from 4 placebo-controlled (one 9-week and three 13-week), fixed-dose studies of adult patients experiencing an acute exacerbation of schizophrenia.1
Significant weight gain has been reported with the use of INVEGA SUSTENNA®.
Clinical monitoring of weight gain is recommended.1
Median exposure was 171 days.1
*Transition baseline to double-blind endpoint.2
Results from the longer-term, placebo-controlled study of adult patients with schizophrenia. Patients were treated for 33 weeks during an open-label stabilization phase with INVEGA SUSTENNA® (39 mg, 78 mg, or 156 mg every 4 weeks after initiation). Patients were then randomized to this same dose or to placebo in a variable-length, double-blind phase. A preplanned interim analysis was conducted after 68 relapse events.1
References: 1. INVEGA SUSTENNA® [Prescribing Information]. Titusville, NJ: Janssen Pharmaceuticals, Inc.; July 2022. 2. Hough D, Gopal S, Vijapurkar U, et al. Paliperidone palmitate maintenance treatment in delaying the time-to-relapse in patients with schizophrenia: a randomized, double-blind, placebo-controlled study. Schizophr Res. 2010, 116(2-3):107-117.