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INVEGA SUSTENNA® Dosing Maintenance | HCP

Fully Initiate INVEGA SUSTENNA® for Schizophrenia in 7 Days
With 2 Initiation Doses—With No Oral Supplementation1


An illustration showing the dosage for days 1 and 8 with no oral supplements needed
  • Both initiation doses must be given in the deltoid muscle
  • For patients who have not taken oral paliperidone, oral risperidone, or injectable risperidone, establish tolerability first
  • Previous oral antipsychotics can be discontinued at the time of initiation of treatment with INVEGA SUSTENNA®
  • To avoid a missed dose, patients may be given the second initiation dose within a ±4-day flexible window

Monthly Maintenance Doses

The first monthly maintenance dose* should be administered 5 weeks after the first injection (regardless of the timing of the second injection)

An illustration showing the dosage for day 36 with no oral supplements needed
  • To avoid a missed dose, monthly maintenance doses may be given within a ±7-day flexible window
  • Utilizing the maintenance dosing window to help avoid missed doses should be considered the exception rather than the rule

*The recommended maintenance dose for the treatment of schizophrenia is 117 mg. Patients may benefit from flexible maintenance dosing options within the available strengths.

Administration notes

  • Each injection must be administered by a healthcare professional
  • Select the appropriate needle size depending on the patient’s weight and injection location
  • Shake the prefilled syringe for at least 10 seconds before administering
Dosing Guide

Download the full Dosing and Administration Guide


Reference: 1. INVEGA SUSTENNA® [Prescribing Information]. Titusville, NJ: Janssen Pharmaceuticals, Inc.; July 2022.